Statement 1 : Acylation of amines gives a monosubstituted product whereas alkylation of amines gives polysubstituted product.
Statement 2 : Acyl group sterically hinders the approach of further acyl groups.

Question

Statement 1 : Acylation of amines gives a monosubstituted product whereas alkylation of amines gives polysubstituted product.

Statement 2 : Acyl group sterically hinders the approach of further acyl groups.

TestHub · Accepted Answer

The Statement 1 is correct: the amide nitrogen is deactivated by resonance (lone pair delocalised over C==O), so acylation stops at monosubstitution, while alkylated nitrogen stays nucleophilic and over-alkylates. The Statement 2 given is wrong — the real cause is resonance deactivation, not steric hindrance. NCERT print key (iii).

Chemistry - AMINES Question with Solution | TestHub

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