Zoology - Principles of Inheritance and Variation Question with Solution | TestHub

Sickle cell anaemia is caused by a change in a single base pair of DNA. Sickle-cell anaemia is the name of a specific form of sickle-cell disease in which there is homozygosity for the mutation that causes HbS. Sickle-cell disease, or sickle-cell anaemia ( or drepanocytosis), is a life-long blood disorder characterized by red blood cells that assume an abnormal, rigid, sickle shape. Sickling decreases the cells flexibility and results in a risk of various complications.