Zoology - Biotechnology and Its Applications Question with Solution | TestHub

ZoologyBiotechnology and Its ApplicationsApplications in MedicineEasy2 minPYQ_2020
ZoologyEasysingle choice

Which of the following statements regarding the structure of pro-insulin and mature insulin is INCORRECT?

(i) Pro-insulin is made up of three polypeptide chains-A, B, and C.

(ii) C-polypeptide chain with 33 amino acids is removed prior to insulin formation.

(iii) Mature insulin is made up of 51 amino acids arranged in two polypeptide chains-A and B.

(iv) Polypeptide chain A has 30 amino acids and polypeptide chain B has 21 amino acids.

(v) Polypeptide chains A and B are interconnected by only one S - S linkage.

Options:

Answer:
C
Solution:

Proinsulin has three polypeptide chains-A, B, C. The mature insulin has onlyA and B.Cpolypeptide is removed before the insulin matures. It has 33 amino acids. Mature insulin has 51 amino acids out of which A polypeptide has 21 amino acids and B has 30 amino acids. Polypeptide A and B are interconnected by two disulfide linkages.

Stream:NTA_ABHYAS_NEETSubject:ZoologyTopic:Biotechnology and Its ApplicationsSubtopic:Applications in Medicine
⏱ 2mℹ️ Source: PYQ_2020

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