Chemistry - Biomolecules Question with Solution | TestHub

The protein hemoglobin $(\mathrm{Hb})$ transports ${\mathrm{O}}_2$ in mammalian blood. Each Hb can bind four ${\mathrm{O}}_2$ molecules. In discussing protein oxygen binding capacity, biochemists use a measure called the P 50 value, defined as the partial pressure of oxygen at which $50\%$ of the protein is saturated. Fetal hemoglobin has a P 50 value of 2.5 kPa and adult hemoglobin has P 50 value of 3.5 kPa . Find out how many times, ${\mathrm{K}}_{\mathrm{PC}}$ is higher in fetus compare to that of adult for below reaction.

$4O(g)+Hb(aq)\rightleftharpoons [Hb(O_2{)}_4](aq)$

Assume that the ratio of Hb and Hb(O₂)₄ concentration remains the same.

(Round off to the nearest integer)