Biology - Principles of Inheritance and Variation Question with Solution | TestHub
Which of the following statements are CORRECT?
Statement (I): Thalassemia is an autosomal, inherited recessive disease.
Statement (II): Haemoglobin molecule is made up of four polypeptide chain - and chains
Statement (III): The synthesis of -chain are controlled by HBA 1 and HBA2 on chromosome 11
Statement (IV): The synthesis of chain is controlled by single gene (HBB) on chromosome 16.
Options:
Answer:
Solution:
Statement (I) is correct as Thalassemia is an autosomal recessive inherited disease.
Statement (II) is correct as the adult haemoglobin molecule consists of four polypeptide chains, which are two and two chains.
Statement (III) is incorrect because the synthesis of the -chain is controlled by two closely linked genes, HBA1 and HBA2, located on chromosome 16, not chromosome 11.
Statement (IV) is incorrect because the synthesis of the -chain is controlled by a single gene, HBB, located on chromosome 11, not chromosome 16.
Therefore, Statements (I) and (II) are correct while (III) and (IV) are incorrect.
Answer: Statement (I) and (II) are correct while (III) and (IV) are incorrect
