People with Kleinfelter's syndrome have 47 chromosomes, including three sex chromosomes (XXY). What is the term to describe the aberration that occurs during meiosis that results in abnormal chro

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People with Kleinfelter's syndrome have 47 chromosomes, including three sex chromosomes (XXY). What is the term to describe the aberration that occurs during meiosis that results in abnormal chromosome number?

TestHub · Accepted Answer

Non-disjunction is the failure of homologous chromosomes or sister chromatids to separate properly during cell division. There are three forms of non-disjunction: failure of a pair of homologous chromosomes to separate in meiosis I, failure of sister chromatids to separate during meiosis II, and failure of sister chromatids to separate during mitosis. Non-disjunction results in daughter cells with abnormal chromosome numbers (aneuploidy).

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