Biology - Molecular Basis of Inheritance Question with Solution | TestHub
In protein synthesis, during elongation of a polypeptide chain, the charged tRNA carrying the aminoacid is received at ___ site and uncharged tRNA is released from ___ site of the ribosome respectively.
Options:
Answer:
Solution:
During the elongation phase of protein synthesis, the ribosome has three specific sites for tRNA binding: the A (aminoacyl) site, the P (peptidyl) site, and the E (exit) site.
The incoming charged tRNA (aminoacyl-tRNA) carrying the next amino acid to be added to the polypeptide chain binds to the A site.
After the peptide bond is formed, the ribosome translocates, shifting the uncharged tRNA to the E site, from where it is released into the cytoplasm.
Therefore, the charged tRNA is received at the 'A' site and the uncharged tRNA is released from the 'E' site.
Answer: 'A' and 'E'
