Zoology - Molecular Basis of Inheritance Question with Solution | TestHub

Erwin Chargaff’s rules:Chargaff’s along with his colleagues, performed base composition studies and put forward certain generalizations for double-stranded DNA, called Chargaff’s rule (Not applicable for single-stranded DNA).
i) Purines and pyrimidines occur in equal amounts.
ii) Purines found in DNA are adenine and guanine. Pyrimidines of DNA are thymine and cytosine.
A + G = T + C
iii)$\frac{A+G}{T+C} = 1$this value is constant for all species.
iv) Base ratio$\frac{A+T}{G+C}$is specific for a species. It is used to identify the species. It is less than one in prokaryotes, e.g., E. coli = 0.92, and more than one in eukaryotes, e.g., Human = 1.52.
v) Sugar deoxyribose and phosphate residues occur in equal number.
vi) Purine adenine is equimolar with pyrimidine thymine
vii) Purine guanine is equimolar with pyrimidine cytosine.