Zoology - Principles of Inheritance and Variation Question with Solution | TestHub
Assertion : Persons suffering from haemophilia fail to produce blood clotting factor VIII. Reason : Prothrombin producing platelets in such persons are found in very low concentration.
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Haemophilia, also called bleeder's disease is a X-linked recessive disorder. The person which contains the recessive gene for haemophilia lacks a normal clotting substance (thromboplastin) in blood. So minor injuries cause continuous bleeding and ultimate death of the person due to hemorrhages. Haemophilia is of two types : type A characterized by lack of antihaemophilic globulin (factor VIII) and type B characterized by a defect in plasma thromboplastic component (factor IX). Prothrombin is an inactive plasma protein and is produced by liver. It helps in blood clotting. It is not produced by platelets.
