Zoology - Molecular Basis of Inheritance Question with Solution | TestHub

The final proof that DNA is the genetic material came from the experiments of Alfred Hershey and Martha Chase (1952). Griffith's experiment proved the existence of genetic material while Avery, MacLeod and McCarty worked to determine the biochemical nature of transforming principle.

Concept enhancer Hershey and Chase during their experiment grew viruses in two mediums, one containing³²P and other³⁵S, when these were allowed to infect bacteria, they observed that viruses containing³²P DNA were radioactive while those with³⁵S protein were not radioactive. Hence, DNA not protein coat entered bacterial cells from viruses.