Zoology - Biotechnology - Principles and Processes Question with Solution | TestHub

DNA ase (or deoxyribonuclease) or simply nuclease is an enzyme which breaks down DNA by hydrolysis of the phosphodiester bonds of its sugar-phosphate back-bone. Depending on the position of hydrolysing phosphodiester bonds, nucleases are of two types: (i) Endonucleases (ii)Exonucleases. Endonucleases hydrolyse internal phosphodiester bonds in a polynucleotide chain (i.e., DNA). While exonucleases hydrolyse terminal phosphodiester bonds in a polynucleotide chain (i.e., DNA).