Zoology - Biotechnology and Its Applications Question with Solution | TestHub
For the treatment of SCID by gene therapy:
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Gene therapy is a group of methods that allows correction of a gene defect that has been diagnosed in an individual.The first gene therapy treatment was given to a girl child who was suffering from SCID where the individual lacked the enzyme ADA or adenosine deaminase. It is an important enzyme for the immunity of the individual. Its deficiency can lead to severe compromise of the immune system. In this process, using a retroviral vector a functional cDNA having the code for ADA is introduced in to the lymphocyte cells which is then returned back to the patient. Since these cells are not immortal, the patient will need regular infusion of modified lymphocytes.
