Zoology - Biotechnology and Its Applications Question with Solution | TestHub

The first clinical gene therapy was given for treating Adenosine deaminase deficiency. It was conducted at Maryland in 1990 on a four year old girl. She was suffering from ADA deficiency. This enzyme is important for formation of immune system in the body. Hence biotechnology principles were applied to treat this condition. A functional ADA gene was introduced ex vivo in the marrow cells through a vector which had functional ADA gene. The treated cells were reintroduced into the patient's marrow.