Eli Lily an American company prepared two DNA sequences corresponding to A and B, chains of human insulin and introduced them in plasmids of E. coil to produce insulin chains. These chains A and B wer

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Eli Lily an American company prepared two DNA sequences corresponding to A and B, chains of human insulin and introduced them in plasmids of E. coil to produce insulin chains. These chains A and B were

TestHub · Accepted Answer

Insulin molecule contains two polypeptide chains: chain A and chain B . Both these chains are linked to each other with the help of disulphide bonds. Thus, after being produced separately, disuplhide bonds will be used for combining the two chains. Insulin is initially present as a prohormone, which has an additional C peptide. This C peptide is removed during maturation of the prohormone to insulin.

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