Eli Lilly, an American company prepared two DNA sequences corresponding to A and B, chains of human insulin, and introduced them in plasmids of E. coli to produce insulin chains. Chains A and B were p

Question

Eli Lilly, an American company prepared two DNA sequences corresponding to A and B, chains of human insulin, and introduced them in plasmids of E. coli to produce insulin chains. Chains A and B were produced separately, extracted and combined by creating

TestHub · Accepted Answer

Human insulin is synthesized as proinsulin and consists of three polypeptide chains A, B, and C. During conversion into functional insulin C polypeptide is removed and A and B polypeptides are joined two disulpide bonds forming functional insulin. The first genetically engineered human insulin was made by an American company Eli Lilly and was marketed by name Humulin.

Zoology - Biotechnology and Its Applications Question with Solution | TestHub

Options:

Doubts & Discussion