Chemistry - Coordination Chemistry Question with Solution | TestHub

ChemistryCoordination ChemistryMiscellaneous/MixedMedium2 minQB
ChemistryMediumsingle choice

Complex which is used as anticancer drug is-

Options:

Answer:
D
Solution:

Identify the drug: The well-known platinum-based coordination complex used in chemotherapy to treat various cancers is cisplatin.

 

Chemical Formula: Its chemical formula is , consisting of a central platinum(II) ion bonded to two amine ligands and two chloride ligands.

 

Geometric Isomerism: The cis-isomer is biologically active because both similar ligands ( and ) are positioned on the same side of the square planar geometry.

 

Mechanism of Action: This specific cis-configuration allows the complex to bind effectively to cellular DNA, forming cross-links that inhibit replication and trigger cancer cell death.

Stream:JEESubject:ChemistryTopic:Coordination ChemistrySubtopic:Miscellaneous/Mixed
⏱ 2mℹ️ Source: QB

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