Chemistry - Coordination Chemistry Question with Solution | TestHub
ChemistryCoordination ChemistryMiscellaneous/MixedMedium2 minQB
ChemistryMediumsingle choice
Complex which is used as anticancer drug is-
Options:
Answer:
D
Solution:
Identify the drug: The well-known platinum-based coordination complex used in chemotherapy to treat various cancers is cisplatin.
Chemical Formula: Its chemical formula is , consisting of a central platinum(II) ion bonded to two amine ligands and two chloride ligands.
Geometric Isomerism: The cis-isomer is biologically active because both similar ligands ( and ) are positioned on the same side of the square planar geometry.
Mechanism of Action: This specific cis-configuration allows the complex to bind effectively to cellular DNA, forming cross-links that inhibit replication and trigger cancer cell death.
Stream:JEESubject:ChemistryTopic:Coordination ChemistrySubtopic:Miscellaneous/Mixed
⏱ 2mℹ️ Source: QB
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