Chemistry - Carboxylic acid and their Derivatives Question with Solution | TestHub
As a way of summarizing consider the reaction of methyllithium a typical organometallic compound with bromoethane a typical halide.
Three different reactions can be predicted.
(I) Nucleophilic substitution (SN2) (organometallic coupling)
(II) Halogen metal exchange:
(III) Bimolecular elimination reaction.
In principle all three of these reaction can compete with one another. How to promote just one of them over the two.
To promote (I) reaction i.e. organometallic coupling organolithium compound should be first converted to lithium dialkyl cuprate by reaction with cuprous iodide because -
S1 : R2CuLi is less basic than RLi.
S2 : R2CuLi has lower affinity for halogen.
S3 : R2CuLi are very effective at coupling with alkyl halide.
S4 : R2CuLi is more basic than RLi so will give less E2 reaction.
S5 : Coupling can even be done with tertiary halides as it follow SET mechanism.
Which of the following above statements are correct?
Options:
Answer:
Solution: