Arrange the following compounds in decreasing orders of rate of exchange of $O^{18}$ with $H_{2} O^{18}$ .
(X) $CCl_{3} CHO$ (Y) $CH_{3} CHO$
(Z) $CH_{3} COCH_{3}$ (W) $CF_{3} COCF_{3}$

Question

Arrange the following compounds in decreasing orders of rate of exchange of O 18 with H 2 ​ O 18 . (X) CCl 3 ​ CHO (Y) CH 3 ​ CHO (Z) CH 3 ​ COCH 3 ​ (W) CF 3 ​ COCF 3 ​

TestHub · Accepted Answer

The rate of O¹⁸ exchange depends on the electrophilicity of the carbonyl carbon. Electron-withdrawing groups increase electrophilicity, enhancing the rate. Order: W > X > Y > Z.

Chemistry - Carbonyl compounds Question with Solution | TestHub

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