How many chiral centers are present in the open-chain form and the α-D-glucopyranose form of D-Glucose, respectively?

Question

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Solution:

A chiral center (stereocenter) is a carbon atom bonded to four different groups.

In the open-chain form of D-Glucose, carbons C2, C3, C4, and C5 are chiral centers, totaling 4.

In the $α$ -D-glucopyranose form, C1 (anomeric carbon), C2, C3, C4, and C5 are chiral centers, totaling 5.

Thus, the answer is 4 and 5, respectively.

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