Following graphs show the effect of change in concentration of substrate on enzyme activity:

Graph - A:

Graph - B:

Graph - C:

Graph - D:

In which of the above curve, the enzyme shows maximum substrate affinity?

Question

TestHub · Accepted Answer

K m indicates the affinity of the enzyme towards its substrate. Km = 1 2 V m a x K m value differs from substrate to substrate because different enzymes differ in their affinity towards different substrates. A high K m indicates low affinity, whereas a low K m shows strong affinity. Out of the given graphs, K m value is lowest in this option and hence shows maximum substrate affinity.

Chemistry - Biomolecules Question with Solution | TestHub

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