Chemistry - ALCOHOL & ETHER Question with Solution | TestHub

Question Explanation:

To find out the compound cannot be cleaved by periodic acid (HIO₄), an oxidizing agent that cleaves

vicinal (1,2-) diols and similar linkages.

Concept:

This question is based on Periodic acid oxidation, glycol cleavage, vicinal diols requirement.

Solution:

Periodic acid (HIO₄ ) cleaves compounds having –CHOH–CHOH–, –CHOH–CO–, or –CO–CO–

linkages — i.e., adjacent carbons each bearing oxygen-containing groups.

If the oxygen atoms are not on adjacent carbons (e.g., separated by a –CH₂– group), no cleavage occurs.

So, Vicinal diol, α – hydroxy carbonyl, α, β– di carbonyl are cleaved by HIO₄ .

Final Answer: The correct options are (A) & (D).