Absence of enzyme phenylalanine hydroxylase causes metabolic disorder as this enzyme is essential for conversion of phenylalanine to __________.

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Phenylketonuria is an inborn error of metabolism inherited as an autosomal recessive trait.

The affected individual lacks the enzyme phenylalanine hydroxylase, which is essential for the conversion of the amino acid phenylalanine into tyrosine.

Due to the absence of this enzyme, phenylalanine accumulates and gets converted into phenylpyruvic acid and other derivatives, leading to mental retardation.

Biology - Principles of Inheritance and Variation Question with Solution | TestHub

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