Biology - Principles of Inheritance and Variation Question with Solution | TestHub

Down's syndrome is a genetic disorder caused by the presence of an additional copy of chromosome 21 (trisomy of 21).

The affected individual is short-statured with a small round head, furrowed tongue, and partially open mouth. Physical, psychomotor, and mental development is retarded, leading to mild to moderate mental retardation and poor skeletal development.

Change in the size and shape of RBCs is a characteristic feature of sickle cell anemia, not Down's syndrome.

Answer: Change in size and shape of RBCs