Biology - Principles of Inheritance and Variation Question with Solution | TestHub
Match disorders given in Column I with their characteristic symptoms in Column II.
| Column I (Disorders) | Column II (Symptoms) |
|---|---|
| (A) Turner's syndrome | (I) Pale yellow skin, dark urine |
| (B) Down's syndrome | (II) Flat and rounded face with flat nose, protruding tongue |
| (C) Sickle cell anaemia | (III) Poorly developed ovaries and breast |
| (D) Thalassemia | (IV) Half moon shaped RBCs |
Choose the correct option
Options:
Answer:
Solution:
Turner's syndrome is caused by the absence of one of the X chromosomes ( with ). Such females are sterile as ovaries are rudimentary and they lack secondary sexual characters like poorly developed breasts.
Down's syndrome is caused by the presence of an additional copy of the chromosome number (trisomy of ). The affected individual has a flat and rounded face, flat nose, and a protruding tongue.
Sickle cell anaemia is an autosome linked recessive trait. Under low oxygen tension, the mutant haemoglobin molecule undergoes polymerization causing the change in the shape of the RBC from biconcave disc to an elongated sickle like (half moon) structure.
Thalassemia is an autosome-linked recessive blood disease characterized by a reduced rate of synthesis of one of the globin chains. Symptoms include anaemia, pale yellow skin, and dark urine due to the destruction of red blood cells.
Thus, the correct matching is A-III, B-II, C-IV, D-I.
Answer: A-III, B-II, C-IV, D-I
