Biology - Neural Control and Coordination Question with Solution | TestHub

When an action potential reaches the axon terminal of a pre-synaptic neuron, it causes a change in membrane voltage (depolarization).

This depolarization leads to the opening of voltage-gated ${\text{Ca}}^{++}$ channels located on the pre-synaptic membrane.

The influx of ${\text{Ca}}^{++}$ ions into the pre-synaptic terminal triggers the synaptic vesicles to move towards and fuse with the plasma membrane.

This fusion results in the release of neurotransmitters into the synaptic cleft via exocytosis.

Answer: opening of ${\text{Ca}}^{++}$ channels due to change in voltage.