Biology - Molecular Basis of Inheritance Question with Solution | TestHub

BiologyMolecular Basis of InheritanceGenetic CodeMedium2 minPYQ_2026
BiologyMediumsingle choice

Using "frame-shift mutation", genetic code is a triplet code was first evidenced by __________.

Options:

Answer:
D
Solution:

Francis Crick and Sydney Brenner provided the first experimental evidence that the genetic code is a triplet code.

They used frame-shift mutations in the rII region of bacteriophage T4 induced by proflavin.

They demonstrated that the insertion or deletion of one or two base pairs altered the reading frame, resulting in a non-functional protein. However, the insertion or deletion of three base pairs restored the reading frame, proving that the genetic code is read in triplets.

Answer: F. H. C. Crick

Stream:MHT_CET_MEDICALSubject:BiologyTopic:Molecular Basis of InheritanceSubtopic:Genetic Code
⏱ 2mℹ️ Source: PYQ_2026

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