60% saturation of Hb with O 2 occurs at normal pH and at pp O 2 ________ mmHg.

Question

60% saturation of Hb with O 2 ​ occurs at normal pH and at pp O 2 ​ ________ mmHg.

TestHub · Accepted Answer

The oxygen-hemoglobin dissociation curve illustrates the relationship between the partial pressure of oxygen ( $pp O_{2}$ ) and the percentage saturation of hemoglobin with oxygen.

Based on the standard physiological oxygen dissociation curve for adult hemoglobin at normal pH ( $7.4$ ) and body temperature, specific reference points are typically observed.

At $pp O_{2} = 27$ mmHg, hemoglobin is $50%$ saturated, which is known as the $P_{50}$ value.

At $pp O_{2} = 30$ mmHg, hemoglobin is approximately $60%$ saturated.

At $pp O_{2} = 40$ mmHg, representing mixed venous blood, hemoglobin is approximately $75%$ saturated.

At $pp O_{2} = 60$ mmHg, hemoglobin is approximately $90%$ saturated.

Therefore, $60%$ saturation of hemoglobin with oxygen occurs at a $pp O_{2}$ of $30$ mmHg.

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