Biology - Body Fluids and Circulation Question with Solution | TestHub

Bilirubin is a yellow pigment formed by the breakdown of haemoglobin from dead red blood cells. Unconjugated bilirubin is fat-soluble and can cross the blood-brain barrier. High levels of this fat-soluble bilirubin are highly toxic to the brain and can cause a severe condition known as kernicterus, which leads to irreversible brain damage, especially in infants. Therefore, monitoring serum bilirubin values holds significant diagnostic importance in jaundice to assess the severity of the condition and prevent neurological complications.

Answer: fat soluble bilirubin is toxic to brain.